The Role of Macrophage Lipophagy in Reverse Cholesterol Transport

Macrophage cholesterol efflux is a central step in reverse cholesterol transport, which helps to maintain cholesterol homeostasis and to reduce atherosclerosis.Lipophagy has recently been identified as a new step in cholesterol Make Up Tools ester hydrolysis that regulates cholesterol efflux, since it mobilizes cholesterol from lipid droplets of ma

read more

Nanosecond pulsed electric field suppresses development of eyes and germ cells through blocking synthesis of retinoic acid in Medaka (Oryzias latipes).

Application of nanosecond pulsed electric fields (nsPEFs) has attracted rising attention in various scientific fields including medical, pharmacological, and biological sciences, although its effects and molecular mechanisms leading to the effects remain poorly understood.Here, we show that a single, high-intensity (10-30 kV/cm), 60-ns PEF exposure

read more

Professional journalism in the age of social media

The article is devoted to analyzing the current state of Cuddlers professional journalism in the era of the flourishing of antisocial networks.The author emphasizes that the context in which professional journalism operates has changed in many respects in the 21st century.These changes are manifold and sometimes contradictory, but they can be summa

read more

Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides.

Microbial natural products constitute a wide variety of chemical compounds, many which can have antibiotic, antiviral, or anticancer properties that make them interesting for clinical purposes.Natural product classes include polyketides (PKs), nonribosomal peptides (NRPs), and ribosomally synthesized and post-translationally modified peptides (RiPP

read more